Hudson Square is a neighborhood in Lower Manhattan, New York City, approximately bounded by Clarkson Street to the north, Canal Street to the south, Varick Street to the east and the Hudson River to the west.^[1] To the north of the neighborhood is Greenwich Village, to the south is TriBeCa, and to the east are the South Village and SoHo.^[2] The area, once the site of the colonial property named Richmond Hill, became known in the 20th century as the Printing District,^[3] and into the 21st century it remains a center of media-related activity, including in advertising, design, communications, and the arts.^[4]

Within the neighborhood is the landmarked Charlton–King–Vandam Historic District, which contains the largest concentration of Federalist and Greek Revival style row houses built during the first half of the 19th century. The most prominent feature within the neighborhood is the Manhattan entrance to the Holland Tunnel. The current tallest structure in the neighborhood is the Dominick condo hotel.